Insulin Guinea Pig anti-Human, Mouse, Polyclonal, Invitrogen
Guinea Pig Polyclonal Antibody
Manufacturer: Invitrogen PA126938
PA1-26938 detects Insulin from human and mouse samples. PA1-26938 has been successfully used in, immunocytochemistry, immunohistochemistry (frozen), and immunohistochemistry (paraffin) procedures. The PA1-26938 immunogen is full length human protein.Insulin is a peptide hormone secreted by beta cells of the pancreatic islets. It regulates carbohydrate, protein and lipid metabolism by enhancing membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides and synthesis of proteins and nucleic acids. Insulin is 51-amino acid polypeptide product produced from a precursor peptide, proinsulin. Proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds and one molecule of C-peptide. Insulin deficiency results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. Insulin is also present in tumors of b-cell origin such as insulinoma.
|PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)|
|Full length human protein.|
|4° C, do not freeze|
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