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Insulin Guinea Pig anti-Human, Polyclonal, Invitrogen™

Guinea Pig Polyclonal Antibody

Manufacturer:  Invitrogen PA129383

Catalog No. PA129383


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Description

Description

PA1-29383 detects insulin from human samples. PA1-29383 has been successfully used in immunohistochemistry (paraffin tissue) applications. A recommended positive control is human pancreas. The PA1-29383 immunogen is purified human insulin conjugated to carrier protein.

Insulin is a peptide hormone secreted by beta cells of the pancreatic islets. It regulates carbohydrate, protein and lipid metabolism by enhancing membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides and synthesis of proteins and nucleic acids. Insulin is 51-amino acid polypeptide product produced from a precursor peptide, proinsulin. Proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds and one molecule of C-peptide. Insulin deficiency results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. Insulin is also present in tumors of b-cell origin such as insulinoma.
Specifications

Specifications

Insulin
Polyclonal
proprietary buffer with no preservative
P01308
Ins
Guinea Pig
IgG
7 mL
4° C, do not freeze
Primary
3630
Immunohistochemistry (Paraffin)
Unconjugated
INS
Liquid
INS
Purified human insulin conjugated to carrier protein
Purified
RUO
Antibody
Polyclonal
Human
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