Insulin, Polyclonal, Invitrogen
Guinea Pig Polyclonal Antibody
Manufacturer: Invitrogen PA136022
Insulin is one of the major regulatory hormones of intermediate metabolism throughout the body. The biological actions of this hormone involve integration of carbohydrate, protein, and lipid metabolism. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage,formation of triglycerides and synthesis of proteins and nucleic acids. Immunocytochemical investigations have localized insulin in the B or b-cells of pancreatic islets of Langerhans. Deficiency of insulin results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. Insulin is also present in tumors of b-cell origin such as insulinoma.For IHC applications, use at a dilution of 1:400-1:800 using FITC, with overnight incubation at 4ºC. A suggested positive control is rat pancreas.Reconstitute with 50-100 ul of distilled water, and dilute further in 0.1M PBS with 1% BSA and 0.1% sodium azide. For long-term storage, aliquot and store at -20ºC.
|Store at 4°C|
|Frozen), Immunohistochemistry (Paraffin/Frozen)|
|whole serum with 0.1% sodium azide|
|P01308, P01315, P01322|
|Human, Porcine, Rat|
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