Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

CD41 Mouse anti-Human, PE, Clone: MEM-06, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA119648

Catalog No. 01-676-375


Add to cart

Description

Description

CD41 (platelet glycoprotein IIb, ITGA2B) is composed of two subunits -120 kDa a, alpha and 23 kDa b, beta- that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. CD41 is also involved in blood coagulation by mediating platelet aggregation. Upon blood vessel damage, CD41 binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during the early stages of hematopoietic differentiation. Diseases associated with CD41 dysfunction include Glansmann Thrombasthenia, and Platelet type-16 bleeding disorder.
Specifications

Specifications

CD41
Monoclonal
PE
ITGA2B
Liquid
ITGA2B
Leucocytes from a patient suffering from a LGL type leukaemia.
Purified
RUO
Antibody
Monoclonal
Human
Flow Cytometry
MEM-06
PBS with 0.2% BSA and 15mM sodium azide
P08514
BDPLT2, CD41, CD41B, GP2B, GPIIb, GT, GTA, HPA3, GPalpha IIb, integrin alpha-IIb, platelet fibrinogen receptor, alpha subunit, platelet membrane glycoprotein IIb, platelet-specific antigen BAK, ITGA2B
Mouse
IgG1
100 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
3674
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit