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ITGA4 Rat anti-Mouse, PE, Clone: 265329, Invitrogen™

Rat Monoclonal Antibody

Manufacturer:  Invitrogen MA523604

Catalog No. PIMA523604


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Description

Description

The integrin alpha 4 (also known as CD49d and ITGA4) belongs to the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha and beta chains. Alpha4 chain associates with either beta1 or beta7 chain. It has been demonstrated that the putative ligand-binding sites of both integrin alpha4beta1 and alpha4beta7 is located on the alpha4 chain. These ligands included Madcam, VCAM, and fibronectin. Madcam is known as the principal ligand for integrin alpha4beta7. Recently it was also demonstrated that HIV-1 envelope can mimic Madcam by binding to and signaling though integrin alpha4beta7, the gut mucosal homing receptor for peripheral T cells.
Specifications

Specifications

ITGA4
Monoclonal
PE
Itga4
Liquid
ITGA4
Mouse myeloma cell line NS0-derived recombit mouse Integrin alpha 4/CD49d Tyr34-Phe976
Protein A/G
RUO
Antibody
Monoclonal
Mouse
Flow Cytometry
265329
Buffered saline solution with BSA and 0.09% sodium azide
Q00651
269C wild type, CD49 antigen-like family member D, VLA-4 subunit alpha, antigen CD49D, alpha-4 subunit of VLA-4 receptor, ITGA4, ITGA-IV
Rat
IgG2A
100 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
16401
Documents
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