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ITGA7 Rat anti-Mouse, FITC, Clone: 334908, Invitrogen™

Rat Monoclonal Antibody

Manufacturer:  Invitrogen MA523653

Catalog No. PIMA523653


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Description

Description

Reactivity with other Integrin alpha 7 isoforms was not tested. In direct ELISAs, no cross-reactivity with recombit mouse Integrin alpha 2, alpha 3, alpha 4, alpha 5, alpha 9, alpha E, alpha X, recombit human Integrin alpha L, or alpha 11 is observed.

Integrins are heterodimers composed of noncovalently associated transmembrane alpha and beta subunits. The 16 alpha and 8 beta subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, collagen and vitronectin. Certain integrins can also bind to soluble ligands such as Fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors, both receptor clustering and ligand occupancy are necessary for the activation of integrinmediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis.
Specifications

Specifications

ITGA7
Monoclonal
FITC
Itga7
Liquid
ITGA7
CHO-derived recombit mouse Integrin alpha 7 Phe34-Pro1036
Protein A/G
RUO
Antibody
Monoclonal
Mouse
Flow Cytometry
334908
Buffered saline solution with BSA and 0.09% sodium azide
Q61738
Integrin alpha-7, Integrin alpha-7 light chain, Integrin alpha-7 70 kDa form, ITGA7, UNQ406/PRO768
Rat
IgG2B
100 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
16404
Documents
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