CD104 Rat anti-Mouse, Clone: 308601, Invitrogen
Rat Monoclonal Antibody
Manufacturer: Invitrogen MA524024
This antibody does not cross-react with recombit mouse Integrin beta 1, beta 2, beta 6, beta 7, or recombit human Integrin beta 3. Reconstitute at 0.5 mg/mL in sterile PBS.Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
|PBS with 5% trehalose and No Preservative|
|CD104 antigen, GP150, integrin beta-4, integrin beta-4 subunit, ITGB4|
|-20° C, Avoid Freeze/Thaw Cycles|
|Flow Cytometry, Immunohistochemistry, Western Blot|
|CHO-derived recombit mouse Integrin beta 4/CD104 Asn29-Ser711|
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