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Integrin beta 7 Rat anti-Mouse, Clone: 332408, Invitrogen™

Rat Monoclonal Antibody

Manufacturer:  Invitrogen MA524061

Catalog No. PIMA524061


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Description

Description

Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.

Integrin beta 7 associates with integrin alpha 4 (CD49d) to form the alpha 4 beta 7 integrin LPAM-1, expressed on intraepithelial lymphocytes. It also associates with alpha E (CD103) to form the alpha E beta 7 integrin HML-1, expressed on T cells adjacent to mucosal epithelium and intraepithelial lymphocytes. Ligands for LPAM-1 include VCAM-1 (CD106), MAdCAM-1 and fibronectin, while the ligand of HML-1 is E-cadherin (CD324). Integrin beta 7 plays an important role in the adhesion of leukocytes to endothelial cells promoting the transmigration of leukocytes to extravascular spaces during the inflammatory response.
Specifications

Specifications

Integrin beta 7
Monoclonal
0.5 mg/mL
PBS with 5% trehalose and No Preservative
P26011
Integrin beta-7, Gut homing receptor beta subunit, ITGB7
Rat
IgG2A
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
16421
Functional Assay
332408
Unconjugated
Itgb7
Lyophilized
ITGB7
CHO-derived recombit mouse Integrin beta 7 Glu20-His722
Protein A/G
RUO
Antibody
Monoclonal
Mouse
Documents
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