Integrin beta 7 Rat anti-Mouse, Clone: 332408, Invitrogen
Rat Monoclonal Antibody
Manufacturer: Invitrogen MA524061
Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.Integrin beta 7 associates with integrin alpha 4 (CD49d) to form the alpha 4 beta 7 integrin LPAM-1, expressed on intraepithelial lymphocytes. It also associates with alpha E (CD103) to form the alpha E beta 7 integrin HML-1, expressed on T cells adjacent to mucosal epithelium and intraepithelial lymphocytes. Ligands for LPAM-1 include VCAM-1 (CD106), MAdCAM-1 and fibronectin, while the ligand of HML-1 is E-cadherin (CD324). Integrin beta 7 plays an important role in the adhesion of leukocytes to endothelial cells promoting the transmigration of leukocytes to extravascular spaces during the inflammatory response.
|Integrin beta 7|
|PBS with 5% trehalose and No Preservative|
|Integrin beta-7, Gut homing receptor beta subunit, ITGB7|
|-20° C, Avoid Freeze/Thaw Cycles|
|CHO-derived recombit mouse Integrin beta 7 Glu20-His722|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok