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MilliporeSigma™ anti-Integrin beta1 (CD29), Clone: EP1041Y, ™ Non-distribution product as customer accommodation.

Manufacturer:  MilliporeSigma™ 041109/DEL

Catalog No. 50-171-223

This item has been discontinued and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

The integrin family of cell adhesion receptors consists of several membrane-associated heterodimers, composed of an α and a β subunit that associate in a non-covalent manner. The structure and functional diversity of the integrin family is based upon the pairing abilities of the individual α and β subunits. Adhesion results in integrin aggregation into structures called focal adhesion plaques, which form the link between the extracellular space and the intracellular cytoskeleton. Signaling from focal adhesions is initiated by the kinases FAK, Pyk2 and ILK. Phosphorylation and cleavage of integrins result in modifications of cell adhesion, permitting physiological processes such as migration, vascular proliferation, and wound repair. Integrin β1, also known as CD29, is a transmembrane glycoprotein that forms complexes with many integrin α subunits, (1 n++, to form functional receptors that bind to specific extracellular matrix proteins.

Host Species: Rabbit
Clone: EP1041Y
Isotype: IgG
Species Reactivity: Human, Rat, Mouse
Epitope: C-terminus
Immunogen: Synthetic peptide corresponding to the residue near the C-terminal of human Integrin β1.
Formula Weight [Chemical]: ~140 -150kDa

Flow Cytometry, Immunohistochemistry (Paraffin), Western Blotting

Specifications

Specifications

Integrin beta1 (CD29)
Unconjugated
Rabbit
IgG
RUO
Primary
Human, Murine, Rat
EP1041Y
Unpurified
Synthetic peptide corresponding to the residue near the C-terminal of human Integrin β1.
100μL
Cell Structure
Monoclonal
Documents
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