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Interferon alpha-2 Mouse anti-Human, Clone: N39, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA135514

Catalog No. 01-671-354


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Description

Description

IFN alpha (Interferon alpha) is a Type I interferon belonging to a family of structurally related, species-specific proteins exclusive to vertebrates. The interaction of IFN-alpha with its receptor component result in the activation of a number of signaling pathways which are mainly involved in innate immune response against viral infection. In humans, the gene for IFN alpha is located on on chromosome 9. The type I interferons consist of 14 different alpha isoforms (subtypes with slightly different specificities), and single beta, omega, epsilon and kappa isoforms. Homologous molecules are found in many species, including rats and mice (and most mammals), and have been identified in birds, reptiles and fish species. IFN alpha is produced primarily by plasmacytoid dendritic cells, is a potent component of the anti-viral innate immune response and modulates adaptive immunity. Diseases associated with the dysfunction of IFN alpha include Hepatitis C and Hepatitis.
Specifications

Specifications

Interferon alpha-2
Monoclonal
0.1 mg/mL
PBS with 0.05% sodium azide
P01563
Interferon-alpha II
Mouse
IgG1, kappa
100 μg
4° C
Primary
3440
ELISA, Neutralization, Western Blot
N39
Unconjugated
IFNA2
Liquid
IFNA2
Purified recombit IFN-alpha 2c.
Purified
RUO
Antibody
Monoclonal
Human
Documents
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