FABP2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA140304
PA1-40304 detects I-FABP from human, rat, mouse, sheep, and swine samples. PA1-40304 recognizes human intestinal fatty acid binding protein (I-FABP) of both natural and recombit origin. PA1-40304 has been successfully used in ELISA and Western blot applications. The PA1-40304 imunogen is human I-FABP.The I-FABP protein is derived from the human FABP2 gene. FABPs are small intracellular proteins (~13-14 kDa) with a high degree of tissue specificity that bind long chain fatty acids. They are abundantly present in various cell types and play an important role in the intracellular utilization of fatty acids, transport and metabolism. There are at least nine distinct types of FABP, each showing a specific pattern of tissue expression. Due to its small size, FABP leaks rapidly out of ischemically damaged necrotic cells leading to a rise in serum levels. Ischemically damaged tissues are characterized histologically by absence (or low presence) of FABP facilitating recognition of such areas. I-FABP is localized in the small bowel epithelium, with highest expression level in the jejunum.
|Human, Mouse, Porcine, Rat|
|ELISA, Immunohistochemistry (Paraffin), Western Blot|
|PBS with 0.1% BSA and 0.02% sodium azide|
|P12104, P02693, P55050|
|Intestinal fatty acid binding protein|
|2169, 14079, 25598|
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