IRAK4, Mouse, Clone: A8A8, Abnova
Mouse monoclonal antibody raised against synthetic phosphopeptide of IRAK4.
Manufacturer: Abnova Corporation MAB2538
This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene. [supplied by RefSeqSequence: VMTSR
|Mouse monoclonal antibody raised against synthetic phosphopeptide of IRAK4.|
|In TBS, pH 7.2 (BSA, 10% Proclin300)|
|Synthetic phosphopeptide corresponding to residues surrounding T345 of human IRAK4.|
|Store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing.
|This antibody recognizes IRAK4 (phospho T345) with a phosphorylated site at Threonine 345. It does not cross-react with non-phosphospecific peptide.|
|Dot Blot, ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot|
|Western Blot (0.1-1 ug/mL) ELISA (0.01-0.1 ug/mL) Immunoprecipitation (2-5 ug/mL) Immunohistochemistry (2-5 ug/mL) The optimal working dilution should be determined by the end user.|
|Bovine, Canine, Human, Murine|
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