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JHDM1D Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA525040

Catalog No. PIPA525040


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Description

Description

JHDM1D histone demethylase that specifically demethylates dimethylated  ft.Lys-9 ft. and  ft.Lys-27 ft. (H3K9me2 and H3K27me2, respectively) of histone H3, thereby playing a central role in histone code. This specifically binds trimethylated  ft.Lys-4 ft. of histone H3 (H3K4me3), affecting histone demethylase specificity: in presence of H3K4me3, it has no demethylase activity toward H3K9me2, while it has high activity toward H3K27me2. This demethylates H3K9me2 in absence of H3K4me3.
Specifications

Specifications

JHDM1D
Polyclonal
PBS with 0.09% sodium azide
Q6ZMT4
KDM7A, histone lysine demethylase JHDM1D, jmjC domain-containing histone demethylation protein 1D, jumonji C domain-containing histone demethylase 1 homolog D, lysine-specific demethylase 7
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
80853
Flow Cytometry, Immunohistochemistry, Western Blot
Unconjugated
KDM7A
Liquid
KDM7A
KLH conjugated synthetic peptide between 290-316 amino acids from the central region of human JHDM1D
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Documents
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