JHDM1D Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA525040
DescriptionJHDM1D histone demethylase that specifically demethylates dimethylated ft.Lys-9 ft. and ft.Lys-27 ft. (H3K9me2 and H3K27me2, respectively) of histone H3, thereby playing a central role in histone code. This specifically binds trimethylated ft.Lys-4 ft. of histone H3 (H3K4me3), affecting histone demethylase specificity: in presence of H3K4me3, it has no demethylase activity toward H3K9me2, while it has high activity toward H3K27me2. This demethylates H3K9me2 in absence of H3K4me3.
|PBS with 0.09% sodium azide|
|KDM7A, histone lysine demethylase JHDM1D, jmjC domain-containing histone demethylation protein 1D, jumonji C domain-containing histone demethylase 1 homolog D, lysine-specific demethylase 7|
|-20° C, Avoid Freeze/Thaw Cycles|
|Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot|
|KLH conjugated synthetic peptide between 290-316 amino acids from the central region of human JHDM1D|
|Protein A, Antigen Affinity Chromatography|
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