JHDM1D Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA525040
DescriptionJHDM1D histone demethylase that specifically demethylates dimethylated ft.Lys-9 ft. and ft.Lys-27 ft. (H3K9me2 and H3K27me2, respectively) of histone H3, thereby playing a central role in histone code. This specifically binds trimethylated ft.Lys-4 ft. of histone H3 (H3K4me3), affecting histone demethylase specificity: in presence of H3K4me3, it has no demethylase activity toward H3K9me2, while it has high activity toward H3K27me2. This demethylates H3K9me2 in absence of H3K4me3.
|PBS with 0.09% sodium azide|
|KDM7A, histone lysine demethylase JHDM1D, jmjC domain-containing histone demethylation protein 1D, jumonji C domain-containing histone demethylase 1 homolog D, lysine-specific demethylase 7|
|-20° C, Avoid Freeze/Thaw Cycles|
|Flow Cytometry, Immunohistochemistry, Western Blot|
|KLH conjugated synthetic peptide between 290-316 amino acids from the central region of human JHDM1D|
|Antigen affinity chromatography|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok