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JMJD3 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA522974

Catalog No. PIPA522974


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Description

Description

The target sequence has 100% sequence homology with rat.

JMJD3 is a histone demethylase that specifically demethylates trimethylated and dimethylated  ft.Lys-27 ft. of histone H3, thereby playing a central role in histone code. It plays a central role in regulation of posterior development by regulating HOX gene expression. JMJD3 is involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation. It has shown to be essential to mammalian epidermal differentiation and is upregulated in prostate cancer.
Specifications

Specifications

JMJD3
Polyclonal
Unconjugated
KDM6B
Liquid
KDM6B
Synthetic peptide made to an internal portion of the mouse protein (within residues 600-650).
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
1 mg/mL
PBS with 0.1% sodium azide; pH 7.4
O15054, Q5NCY0
JMJD3, jmjC domain-containing protein 3, jumonji domain containing 3, histone lysine demethylase, jumonji domain-containing protein 3, lysine demethylase 6B, lysine-specific demethylase 6B
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
216850, 23135
Documents
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