JMJD3 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA522974
The target sequence has 100% sequence homology with rat.JMJD3 is a histone demethylase that specifically demethylates trimethylated and dimethylated ft.Lys-27 ft. of histone H3, thereby playing a central role in histone code. It plays a central role in regulation of posterior development by regulating HOX gene expression. JMJD3 is involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation. It has shown to be essential to mammalian epidermal differentiation and is upregulated in prostate cancer.
|Synthetic peptide made to an internal portion of the mouse protein (within residues 600-650).|
|Antigen affinity chromatography|
|Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot|
|PBS with 0.1% sodium azide; pH 7.4|
|JMJD3, jmjC domain-containing protein 3, jumonji domain containing 3, histone lysine demethylase, jumonji domain-containing protein 3, lysine demethylase 6B, lysine-specific demethylase 6B|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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