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Kallikrein 6 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA522970

Catalog No. PIPA522970


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Description

Description

The target sequence has 85% sequence homology with canine, 82% sequence homology with equine and 80% sequence homology with bovine.

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Kallikrein 6, or KLK6, shows activity against amyloid precursor protein, myelin basic protein, gelatin, casein and extracellular matrix proteins such as fibronectin, laminin, vitronectin and collagen. It degrades alpha-synuclein and prevents its polymerization, indicating that it may be involved in the pathogenesis of Parkinson disease and other synucleinopathies. KLK6 may be involved in regulation of axon outgrowth following spinal cord injury. KLK6 has also been shown to promote cell proliferation, migration, and invasion and is upregulated in several types of cancers including colon and ovarian cancers.
Specifications

Specifications

Kallikrein 6
Polyclonal
whole serum with 0.1% sodium azide
Q92876
Bssp, Klk7, PRSS18, PRSS9, SP59, hK6, kallikrein-6, neurosin, protease M, serine protease 18, serine protease 9, zyme
Rabbit
IgG
RUO
Antibody
Polyclonal
Human
Immunocytochemistry, Immunofluorescence, Western Blot
Unconjugated
KLK6
Liquid
KLK6
Full length human KLK6 protein expressed in E. coli.
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
5653
Documents
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