KChIP3 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA511665
DescriptionKChIP3 is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. This protein is also shown to function as a calcium-regulated transcriptional repressor, and to interact with presenilins. Mutations in the presenilin genes have been implicated in Alzheimer ft.s disease. Due to utilization of an alternate in-frame translation start codon, the gene for this protein encodes two isoforms with different sizes.
|PBS with 0.09% sodium azide|
|KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human KChIP3|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|-20° C, Avoid Freeze/Thaw Cycles|