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Kir6.2 (KCNJ11) Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA526218

Catalog No. PIPA526218


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Description

Description

This antibody is predicted to react with rabbit based on sequence homology.

ATP-sensitive potassium (K(ATP)) channels are found in endocrine cells, neurons and both smooth and striated muscle, where they play an important role in controlling insulin secretion and vascular tone, and protect neurons under metabolic stress. Kir6.2 is a member of the inward rectifier potassium channel family, which is characterised by a greater tendency to allow potassium flow into the cell rather than out of it. It associates with the sulphonylurea receptor SUR1/ABCC8 to form a subfamily of K(ATP) channels that, when mutated or misregulated, are associated with forms of hyperinsulinemic hypoglycemia, neonatal diabetes, or pre-disposition to type 2 diabetes mellitus.
Specifications

Specifications

Kir6.2 (KCNJ11)
Polyclonal
Unconjugated
KCNJ11
Liquid
KCNJ11
KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human KCNJ11
Antigen Affinity Chromatography, Protein A
RUO
Antibody
Polyclonal
Human, Mouse
Flow Cytometry, Western Blot
0.5 mg/mL
PBS with 0.09% sodium azide
Q14654, Q61743
BIR, HHF2, IKATP, KIR6.2, PHHI, TNDM3, ATP-sensitive inward rectifier potassium channel 11, beta-cell inward rectifier subunit, inward rectifier K(+) channel Kir6.2, inwardly rectifying potassium channel KIR6.2, potassium channel inwardly rectifing subfamily J member 11, potassium channel, inwardly
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
16514, 3767
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