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Kinesin 5A Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA520421

Catalog No. PIPA520421


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Description

Description

A suggested positive control is K562 cell lysate. PA5-20421 can be used with blocking peptide PEP-0538.

The kinesin superfamily proteins (KIFs) are microtubule-dependent motors that slide along microtubules and transport cellular organelles and mRNA to different parts of the cell. In neurons, KIF5 performs this role in an anterograde fashion from the neuronal cell body to axonal or dendritic terminals. KIF5 was initially differentiated from the ubiquitously expressed kinesin as being highly enriched in subsets of neurons and selectively concentrated in the cell body. KIF5 has at least three known isoforms; this antibody recognizes all three. Mutations in one of the isoforms of KIF5 (KIF5A) are thought to be involved in hereditary spastic paraplegias.
Specifications

Specifications

Kinesin 5A
Polyclonal
Unconjugated
KIF5A
Liquid
KIF5A
A 20 amino acid peptide from near the center of human KIF5.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunocytochemistry, Immunofluorescence, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q12840, P33175, Q6QLM7
D12S1889, MY050, NKHC, SPG10; KIF5A variant protein; kinesin heavy chain isoform 5A; kinesin heavy chain neuron-specific 1; kinesin, heavy chain, neuron-specific; neuronal kinesin heavy chain
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
16572, 314906, 3798
Documents
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