Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Kindlin 3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA520598

Catalog No. PIPA520598

Add to cart



A suggested positive control is rat spleen tissue lysate. PA5-20598 can be used with blocking peptide PEP-0718.

The three KINDLINs are a novel family of focal adhesion proteins, localizing to integrin adhesion sites. The KINDLIN proteins are composed of a centrally located FERM domain interrupted by a pleckstrin homology (PH) domain. KINDLIN1 and KINDLIN2 have been shown to play an essential role in integrin-mediated adhesion and spreading. In contrast to the widely expressed KINDLIN1 and KINDLIN2, KINDLIN3 is restricted to hematopoietic cells and is particularly abundant in megakaryocytes and platelets. Several reports describe a transcriptional misregulation of KINDLINs in various types of cancer. A recent study demonstrates that KINDLIN3 is essential for platelet integrin activation and subsequent integrin outside-in signaling, suggesting it may serve as a potential target for the design of therapeutics aimed at specifically disrupting integrin activation in platelets and leukocytes.


Kindlin 3
A 19 amino acid peptide near the carboxy terminus of the human KINDLIN3.
Antigen affinity chromatography
Human, Mouse, Rat
Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q86UX7, Q8K1B8
KIND3, MIG-2, MIG2B, UNC112C, URP2, URP2SF; MIG2-like protein; UNC-112 related protein 2; fermitin family homolog 3; kindlin 3; unc-112-related protein 2
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
108101, 309186, 83706
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit