KIF2A Rabbit anti-Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA1640
PA1-640 detects kinesin 2 (KIF2) from mouse tissues. PA1-640 has been successfully used in Western blot procedures. By Western blot, this antibody detects an ~95 kDa protein representing KIF2 from mouse brain homogenate. PA1-640 immunizing peptide corresonds to amino acid residues 1-11 from mouse KIF2. This sequence is completely conserved in human KIF2. PA1-640 immunizing peptide (Cat. No. PEP-040) is available for use in neutralization and control experiments.Kinesins are a superfamily of microtubule-associated motor proteins involved in a variety of cellular processes including membranous organelle transport and cell division. Kinesin has been found in a variety of organisms and cell types and is subject to spatial and temporal regulation. These proteins have a modular structure which includes a conserved motor domain of approximately 350 amino acids, which is responsible for microtubule binding and ATP hydrolysis. In addition to the motor domain, subfamily members share common domain organization, exhibit sequence similarity, motility properties, and cellular functions outside of the motor domain. An expansive phylogenetic tree of kinesins and kinesin-related proteins (KRPs) has been assembled based on this information.
|Synthetic Peptide: M(1) V T S L N E D N E S(11) C|
|Antigen affinity chromatography|
|PBS with 1mg/mL BSA and 0.05% sodium azide|
|-20° C, Avoid Freeze/Thaw Cycles|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok