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Kinesin 5B Mouse anti-Human, Mouse, Porcine, Rat, Clone: KN-02, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA119352

Catalog No. 01-676-108


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Description

Description

Kinesin belongs to the group of microtubule-associated motor proteins known to convert chemical energy released from nucleoside triphosphates (preferentially from ATP) into mechanical energy. Conventional kinesin, member of the kinesin superfamily comprising more than 100 proteins, is involved in the anterograde vesicle transport in neuronal cells. Kinesin purified from mammalian brain homogenates is a heterotetramer consisting of two heavy (120 to 130 kDa) and two light chains (60 to 70 kDa), resulting in a molecular mass about 400 kDa. Each heavy chain contains an N-terminal globular motordomain with both a microtubule-binding site and an ATPase active center, stalk region responsible for heavy chain dimerization and finally C-terminal globular tail domain, which is implicated in cargo binding. Light chains may have a regulatory function.
Specifications

Specifications

Kinesin 5B
Monoclonal
1 mg/mL
TBS with 15mM sodium azide; pH 8
P33176, Q61768, Q2PQA9
KINH, KNS, KNS1, UKHC
Mouse
IgM
100 μg
4° C, do not freeze
Primary
117550, 16573, 3799, 595132
Immunocytochemistry, Immunofluorescence
KN-02
Unconjugated
KIF5B
Liquid
KIF5B
Enriched fraction of porcine brain kinesin.
Purified
RUO
Antibody
Monoclonal
Human, Mouse, Porcine, Rat
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