Kininogen 1 Rat anti-Mouse, Clone: 288422, Invitrogen
Rat Monoclonal Antibody
Manufacturer: Invitrogen MA523988
In Western blots, reacts with the full length mouse Kininogen (aa 21-661), but not with the light chain alone. In Western blots, no cross-reactivity with recombit human (rh) Cystatin D, F, SA, SN, recombit mouse (rm) Cystatin A, B, C, E/M, rmCystatin/Stefin Homolog, rmFetuin A, rhFetuin B, rmHPRG, rhKininogen, or rhKininostatin is observed. Reconstitute at 0.5 mg/mL in sterile PBS.This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.
|PBS with 5% trehalose and No Preservative|
|BDK, KNG, HMWK, alpha-2-thiol proteinase inhibitor, bradykinin, fitzgerald factor, high molecular weight kininogen, kininogen-1, williams-Fitzgerald-Flaujeac factor|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunoprecipitation, Western Blot|
|Mouse myeloma cell line NS0-derived recombit mouse Kininogen Glu21-Ser661|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok