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KLRA2 Rabbit anti-Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA520687

Catalog No. PIPA520687


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Description

Description

A suggested positive control is mouse spleen tissue lysate. PA5-20687 can be used with blocking peptide PEP-0803.

KLRA2 (also known as Ly49B) is a member of the LY49 family of receptors in Natural Killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA2 is thought to be an inhibitory receptor and associates with the protein tyrosine phosphatases SHP1, SHP2, and SHIP in transfected cells. This antibody is predicted to not cross-react with other LY49 receptors.
Specifications

Specifications

KLRA2
Polyclonal
Unconjugated
Klra2
Liquid
KLRA2
A 14 amino acid peptide near the carboxy terminus of mouse KLRA2.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Mouse, Rat
Immunofluorescence, Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q60660
Klra30, Ly49b; NK cell inhibitory receptor Klra2; T-cell surface glycoprotein Ly-49B; T-cell surface glycoprotein Ly49b; killer cell lectin-like receptor 2; killer cell lectin-like receptor subfamily A member 30; ly-49b; lymphocyte antigen 49b; membrane protein Ly49b
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
16633, 494193
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