KLRA3 Rabbit anti-Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA520676
A suggested positive control is mouse brain tissue lysate. PA5-20676 can be used with blocking peptide PEP-0794.KLRA3 (also known as Ly49C) is a member of the LY49 family of receptors in Natural Killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA3 is thought to be an inhibitory receptor, recognizing peptide -receptive H-2Kb.
|A 14 amino acid peptide near the carboxy terminus of mouse KLRA3.|
|Antigen affinity chromatography|
|PBS with 0.02% sodium azide|
|LY49I1, Ly49I; Ly49I receptor|
|Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
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