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KLRA3 Rabbit anti-Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA520676

Catalog No. PIPA520676


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Description

Description

A suggested positive control is mouse brain tissue lysate. PA5-20676 can be used with blocking peptide PEP-0794.

KLRA3 (also known as Ly49C) is a member of the LY49 family of receptors in Natural Killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA3 is thought to be an inhibitory receptor, recognizing peptide -receptive H-2Kb.
Specifications

Specifications

KLRA3
Polyclonal
Unconjugated
Klra3
Liquid
KLRA3
A 14 amino acid peptide near the carboxy terminus of mouse KLRA3.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Mouse, Rat
Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q64329
LY49I1, Ly49I; Ly49I receptor
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
16634
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