Ku70 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA527538
PA5-27538 targets Ku70 in IF, IHC (P), and WB applications and shows reactivity with Human samples. The PA5-27538 immunogen is recombit fragment corresponding to a region within amino acids 366 and 607 of Human Ku70. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.
|Recombit fragment corresponding to a region within amino acids 366 and 607 of Human Ku70|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot|
|PBS with 20% glycerol and 0.025% ProClin 300; pH 7|
|CTC75, CTCBF, G22P1, KU70, ML8, TLAA, 5′-dRP lyase Ku70, 5′-deoxyribose-5-phosphate lyase Ku70, 70 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 1, ATP-dependent DNA helicase II 70 kDa subunit, ATP-dependent DNA helicase II, 70 kDa subunit, CTC box binding factor 75 kDa subunit, CT|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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