Lamin B2 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA529121
PA5-29121 targets Lamin B2 in IF, IHC (P), and WB applications and shows reactivity with Human samples. The PA5-29121 immunogen is recombit protein fragment corresponding to a region within amino acids 277 and 560 of Human Lamin B2. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B2. This gene is in a head-to-tail orientation with the gene for the translocase of inner mitochondrial membrane 13 homolog gene.
|Recombit protein fragment corresponding to a region within amino acids 277 and 560 of Human Lamin B2|
|Antigen affinity chromatography|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7|
|LAMB2, LMN2, lamin-B2|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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