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Laminin alpha-3 Mouse anti-Human, Clone: 546215, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA524246

Catalog No. PIMA524246


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Description

Description

In direct ELISAs, no cross reactivity with recombit human Laminin alpha 1, beta 1, gamma 2, or recombit mouse Laminin alpha 4 is observed. Reconstitute at 0.5 mg/mL in sterile PBS.

The protein encoded by this gene belongs to the laminin family of secreted molecules. Laminins are heterotrimeric molecules that consist of alpha, beta, and gamma subunits that assemble through a coiled-coil domain. Laminins are essential for formation and function of the basement membrane and have additional functions in regulating cell migration and mechanical signal transduction. This gene encodes an alpha subunit and is responsive to several epithelial-mesenchymal regulators including keratinocyte growth factor, epidermal growth factor and insulin-like growth factor. Mutations in this gene have been identified as the cause of Herlitz type junctional epidermolysis bullosa and laryngoonychocutaneous syndrome. Alternative splicing and alternative promoter usage result in multiple transcript variants. [provided by RefSeq, Dec 2014].
Specifications

Specifications

Laminin alpha-3
Monoclonal
0.5 mg/mL
PBS with 5% trehalose and No Preservative
Q16787
Epiligrin, LAMA3, Laminin-5
Mouse
IgG1
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
3909
Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
546215
Unconjugated
LAMA3
Lyophilized
LAMA3
CHO-derived recombit human Laminin alpha 3/Laminin-5 (aa 21-1713)
Protein A/G
RUO
Antibody
Monoclonal
Human
Documents
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