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Laminin gamma-1 Mouse anti-Human, Clone: M1, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA519253

Catalog No. PIMA519253


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Description

Description

Peptide Sequence: MNKRRTSHRI WKNKLPEYMR RPKGPVTKLW RSMPAWLS

Laminins are essential and abundant structural non-collagenous glycoproteins localizing to basement membranes. Basement membranes (cell-associated extracellular matrices (ECMs)) are polymers of Laminins with stabilizing Type IV Collagen networks, Nidogen and several proteoglycans. Basement membranes are found under epithelial layers, around the endothelium of blood vessels, and surrounding muscle, peripheral nerve and fat cells. Formation of basement membranes influences cell proliferation, phenotype, migration, gene expression and tissue architecture. Each Laminin is a heterotrimer of alpha, beta and gamma chain subunits that undergoes cell-secretion and incorporation into the ECM. Laminins can self-assemble, bind to other matrix macromolecules and have unique and shared cell interactions mediated by Integrins, dystroglycan and cognate Laminin receptors. The human Laminin gamma-1 gene maps to chromosome 1q31 and is ubiquitously expressed in tissues that produce basement membranes.
Specifications

Specifications

Laminin gamma-1
Monoclonal
0.26 mg/mL
PBS with no preservative; pH 7.4
P11047
S-LAM beta, S-laminin subunit beta, laminin B1s chain, laminin S, laminin subunit beta-2, laminin-11 subunit beta, laminin-14 subunit beta, laminin-15 subunit beta, laminin-3 subunit beta, laminin-4 subunit beta, laminin-7 subunit beta, laminin-9 subunit beta
Mouse
IgG2a, kappa
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
3915
ELISA, Proximity Ligation Assay (PLA), Western Blot
M1
Unconjugated
LAMC1
Liquid
LAMC1
LAMC1 (AAH15586, 1 a.a. ∽ 38 a.a) full-length recombit protein with GST tag. MW of the GST tag alone is 26 KDa.
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Documents
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