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LAMP1 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA1654A

Catalog No. PA1654A


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Description

Description

PA1-654A detects Lamp1 from human samples. PA1-654A has been successfully used in immunofluorescence and Western blotting procedures. In immunofluorescence procedures, this antibody stains Lamp1 in HeLa cells resulting in perinuclear staining. The PA1-654A immunogen is a synthetic peptide corresponding to residues C K(407) R S H A G Y Q T I(416) of human LAMP1. This region is completely conserved between human, mouse and rat.

Lysosomes are membrane-bound vacuoles which play a critical role in cellular metabolism. These organelles participate in endocytosis, the synthesis and assembly of acid hydrolases, act as sites for digestion of foreign materials and for specialized autolytic cellular processes. Membrane-associated glycoproteins have an important role in normal lysosomal function. Lamp1, also known as lysosome associated membrane protein 1, is a heavily glycosylated membrane protein of the lysosome. It contains a putative signal peptide, 18 sites for N-linked glycosylation, a single membrane-spanning segment and a short (11 amino acid) cytosolic tail.
Specifications

Specifications

LAMP1
Polyclonal
Unconjugated
LAMP1
Liquid
LAMP1
Synthetic peptide corresponding to residues C K(407) R S H A G Y Q T I(416) of human LAMP1.
Affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunocytochemistry, Immunofluorescence, Western Blot
1 mg/mL
PBS with 0.05% sodium azide; pH 7.4
P11279
CD107a, LAMPA, LGP120, CD107 antigen-like family member A, LAMP-1, lysosome-associated membrane glycoprotein 1, lysosome-associated membrane protein 1
Rabbit
IgG
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
3916
Documents
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