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LAT Mouse anti-Human, Clone: LAT-01, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA119307

Catalog No. 01-676-063


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Description

Description

This antibody will not cross-react with mouse.

LAT (Linker for Activation of T cells) is a 36-38 kDa double-palmitoylated transmembrane adaptor protein expressed by T cells, pre-B cells, NK cells, mast cells and platelets. After immunoreceptor triggering, LAT becomes multiply tyrosine-phosphorylated by Syk-, Src-, or Tec-family kinases, providing docking sites for downstream signaling molecules. LAT is essential for TCR-dependent T cell- and FcepsilonRI-dependent mast cell activation, as well as for maturation of early thymocytes. It is also involved in NK cell signaling and platelet activation.
Specifications

Specifications

LAT
Monoclonal
1 mg/mL
PBS with 15mM sodium azide; pH 7.4
O43561
Linker for activation of T cells, ORC3L
Mouse
IgG1
100 μg
4° C, do not freeze
Primary
27040
Flow Cytometry, Immunoprecipitation, Western Blot
LAT-01
Unconjugated
LAT
Liquid
LAT
Bacterially produced recombit polypeptide corresponding to the entire cytoplasmic domain of human LAT
Protein A
RUO
Antibody
Monoclonal
Human
Documents
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