LAT Goat anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Goat Polyclonal Antibody
Manufacturer: Invitrogen PA19063
DescriptionThe protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms.
|Synthetic peptide corresponding to the C terminus amino acids GAPDYENLQELN.|
|Antigen affinity chromatography|
|Human, Mouse, Rat|
|peptide-ELISA, Western Blot|
|TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3|
|O43561, O54957, O70601|
|LAT; linker for activation of T cells; LAT1; pp36; 36 kDa phospho-tyrosine adaptor protein|
|-20° C, Avoid Freeze/Thaw Cycles|
|16797, 27040, 81511|
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