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LAT Goat anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Goat Polyclonal Antibody

Manufacturer:  Invitrogen PA19063

Catalog No. 01-674-647


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Description

Description

The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms.
Specifications

Specifications

LAT
Polyclonal
Unconjugated
LAT
Liquid
LAT
Synthetic peptide corresponding to the C terminus amino acids GAPDYENLQELN.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
peptide-ELISA, Western Blot
0.5 mg/mL
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
O43561, O54957, O70601
LAT; linker for activation of T cells; LAT1; pp36; 36 kDa phospho-tyrosine adaptor protein
Goat
IgG
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
16797, 27040, 81511
Documents
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