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Latexin Rabbit anti-Bovine, Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523253

Catalog No. PIPA523253


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Description

Description

Latexin, the only endogenous specific inhibitor known for zinc-dependent metallocarboxypeptidases, is a 222 amino acid protein belonging to the protease inhibitor I47 (latexin) family. Human latexin is an elongated molecule with N- and C-terminal domains that each consist of an alpha helix enveloped by a curved beta sheet and the two domains are separated by a connecting segment. Latexin is a hardly reversible, non-competitive, and potent inhibitor of CPA1, CPA2 and CPA4 but is less potent against other mammalian carboxypeptidases, and it does not inhibit enzymes of other carboxypeptidase classes like metallopeptidases or serine proteases. In rat, Latexin may be used as a molecular marker for the regional specification of the neocortex. It is expressed in most tissues with high expression in brain, lung and digestive tract.
Specifications

Specifications

Latexin
Polyclonal
Unconjugated
LXN
Liquid
LXN
Synthetic peptide (202 HPQYGTKVKHNSRLPKEV 219) of Latexin protein.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Bovine, Human, Mouse, Rat
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
0.5 mg/mL
PBS with 0.05% BSA and 0.05% sodium azide
Q9BS40, P70202, Q64361
ECI, TCI, MUM, endogenous carboxypeptidase inhibitor, tissue carboxypeptidase inhibitor
Rabbit
IgG
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
17035, 56925, 59073, 781644
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