LEF1 Mouse anti-Human, Mouse, Clone: REMB6, Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA112421
A suggested positive control for this product is Jurkat cell lysate.Lymphoid Enhancer Factor -1 is a transcription factor of the High Mobility Group of DNA binding proteins. It is one member of a family of four proteins referred to as LEF/TCF transcription factors (LEF-1, TCF-1, TCF-3 and TCF-4). These factors play a crucial role in WNT/WIngless signaling, a signal transduction cascade that directs cell differentiation. Aberrant activation of the WNT/Wingless pathway is also a root cause in the genesis of certain cancers such as colon cancer, melanoma and breast cancer.
|PBS with 0.08% sodium azide|
|HMG Binding Domain|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|Full-length recombit LEF-1 protein.|
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