LGI1 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA528291
PA5-28291 targets LGI1 in WB applications and shows reactivity with Human samples. The PA5-28291 immunogen is recombit fragment corresponding to a region within amino acids 178 and 425 of Human LGI1. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.This gene is rearranged as a result of translocations in glioblastoma cell lines. The protein contains a hydrophobic segment representing a putative transmembrane domain with the amino terminus located outside the cell. It also contains leucine-rich repeats with conserved cysteine-rich flanking sequences. This gene is predomitly expressed in neural tissues and its expression is reduced in low grade brain tumors and significantly reduced or absent in maligt gliomas. Mutations in this gene result in autosomal domit lateral temporal epilepsy.
|Recombit fragment corresponding to a region within amino acids 178 and 425 of Human LGI1|
|Antigen affinity chromatography|
|0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7|
|ADLTE, ADPAEF, EPITEMPIN, EPT, ETL1, IB1099, epitempin-1, leucine-rich glioma-inactivated protein 1|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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