LGI1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA520491
A suggested positive control is Hela cell lysate. PA5-20491 can be used with blocking peptide PEP-0611.The leucine-rich, glioma inactivated gene 1 (LGI1) was first identified as a candidate tumor suppressor gene for glioma and may play a role in other cancers. LGI1 is a member of a family of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 serves as a ligand to ADAM22, a metalloprotease localized at the synapse. Mutations in LGI1 account for nearly half of autodomit lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predomit auditory symptoms. Two isoforms of LGI1 are known to exist; this LGI1 antibody will recognize only the longer form.
|A 14 amino acid peptide from near the center of human LGI1.|
|Antigen affinity chromatography|
|Human, Mouse, Rat|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot|
|PBS with 0.02% sodium azide|
|O95970, Q9JIA1, Q8K4Y5|
|UNQ775/PRO1569, EPITEMPIN, EPT, ETL1, IB1099; epitempin-1; leucine-rich glioma-inactivated protein 1|
|Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|252892, 56839, 9211|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok