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LIME Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA135994

Catalog No. 01672497


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Description

Description

LIME (Lck-interacting molecule) is a new raft-associated adaptor protein involved in regulation of T cell activation by coreceptors. LIME becomes tyrosine phosphorylated after cross-linking of the CD4 or CD8 coreceptors. Phospho-LIME associates with the Src family kinase Lck and its negative regulator, Csk. Ectopic expression of LIME in Jurkat T cells results in an increase of Csk in lipid rafts, increased phosphorylation of Lck and higher Ca2+ response to CD3 stimulation.
Specifications

Specifications

LIME
Polyclonal
Unconjugated
LIME1
Liquid
LIME1
Residues 141-295 of human LIME.
Purified
RUO
Antibody
Polyclonal
Human
Western Blot
1 mg/mL
PBS with 15mM sodium azide; pH 7.4
Q9H400
Lck-interacting molecule
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
54923
Documents
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