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LIPG Rabbit anti-Bovine, Human, Mouse, Non-human primate, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA132483

Catalog No. PIPA132483


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Description

Description

PA1-32483 detects Lipase from bovine, rat, mouse, human and Non-human primate samples. PA1-32483 has been successfully used in immunohistochemistry (paraffin tissue), Western blot applications. The PA1-32483 immunogen is: Synthetic peptide surrounding amino acid 22 of human Endothelial Lipase. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

LIPG (Lipase G, Endohelial type) is an endothelial lipase which is a novel member of the lipoprotein lipase gene family. LIPG is synthesized by endothelial cells and functions at the site of synthesis. LIPG most likely plays a physiological role in modulating lipoprotein metabolism. Overexpressed LIPG has been shown to reduce HDL cholesterol levels, whereas an LIPG deficiency appears to be effective in elevating HDL cholesterol levels in animals. LIPG has substantial phospholipase activity and may be involved in lipoprotein metabolism and vascular biology. Also, LIPG is designated a member of the TG lipase family by its sequence and characteristic lid region which provides substrate specificity for enzymes of the TG lipase family. LIPG is a carboxyl esterase that hydrolyzes high density lipoproteins, emulsifies triglycerides, is essential for the efficient digestion of dietary fats and can bind to heparin.
Specifications

Specifications

LIPG
Polyclonal
Unconjugated
LIPG
Liquid
LIPG
Synthetic peptide surrounding amino acid 22 of human Endothelial Lipase.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Bovine, Human, Mouse, Non-human primate, Rat
Immunohistochemistry (Paraffin), Western Blot
0.5 mg/mL
PBS with 1% BSA, 50% glycerol and 0.01% thimerosal; pH 7.2
Q9Y5X9, Q9WVG5, Q8VBX1
lipase
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
16891, 291437, 509808, 9388
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