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LIS1 Mouse anti-Human, Clone: 5A5, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA519522

Catalog No. PIMA519522


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Description

Description

Peptide Sequence: MVLSQRQRDE LNRAIADYLR SNGYEEAYSV FKKEAELDVN EELDKKYAGL LEKKWTSVIR LQKKVMELES KLNEAKEEFT SGGPLGQKRD PKEWIPRPPE KYALSGHRSP

This locus was identified as encoding a gene that when mutated or lost caused the lissencephaly associated with Miller-Dieker lissencephaly syndrome. This gene encodes the non-catalytic alpha subunit of the intracellular Ib isoform of platelet-activating factor acteylhydrolase, a heterotrimeric enzyme that specifically catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist: one composed of multiple subunits, the other, a single subunit. In addition, a single-subunit isoform of this enzyme is found in serum.
Specifications

Specifications

LIS1
Monoclonal
1 mg/mL
PBS with no preservative; pH 7.4
P43034
LIS1, LIS2, MDCR, MDS, PAFAH; LIS-1; PAF acetylhydrolase 45 kDa subunit; PAF-AH 45 kDa subunit; PAF-AH alpha; PAFAH alpha; lissencephaly 1 protein; lissencephaly-1 protein; platelet-activating factor acetylhydrolase IB subunit alpha; platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit (45kD); platelet-activating factor acetylhydrolase, isoform Ib, subunit 1 (45kDa)
Mouse
IgG2a, kappa
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
5048
ELISA, Immunocytochemistry, Immunofluorescence, Western Blot
5A5
Unconjugated
PAFAH1B1
Liquid
PAFAH1B1
PAFAH1B1 (NP_000421, 1 a.a. ∽ 110 a.a) partial recombit protein with GST tag. MW of the GST tag alone is 26 KDa.
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Documents
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