LIS1 Mouse anti-Human, Clone: 5A5, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA519522
Peptide Sequence: MVLSQRQRDE LNRAIADYLR SNGYEEAYSV FKKEAELDVN EELDKKYAGL LEKKWTSVIR LQKKVMELES KLNEAKEEFT SGGPLGQKRD PKEWIPRPPE KYALSGHRSPThis locus was identified as encoding a gene that when mutated or lost caused the lissencephaly associated with Miller-Dieker lissencephaly syndrome. This gene encodes the non-catalytic alpha subunit of the intracellular Ib isoform of platelet-activating factor acteylhydrolase, a heterotrimeric enzyme that specifically catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist: one composed of multiple subunits, the other, a single subunit. In addition, a single-subunit isoform of this enzyme is found in serum.
|PBS with no preservative; pH 7.4|
|LIS1, LIS2, MDCR, MDS, PAFAH; LIS-1; PAF acetylhydrolase 45 kDa subunit; PAF-AH 45 kDa subunit; PAF-AH alpha; PAFAH alpha; lissencephaly 1 protein; lissencephaly-1 protein; platelet-activating factor acetylhydrolase IB subunit alpha; platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit (45kD); platelet-activating factor acetylhydrolase, isoform Ib, subunit 1 (45kDa)|
|-20° C, Avoid Freeze/Thaw Cycles|
|ELISA, Immunocytochemistry, Immunofluorescence, Western Blot|
|PAFAH1B1 (NP_000421, 1 a.a. ∽ 110 a.a) partial recombit protein with GST tag. MW of the GST tag alone is 26 KDa.|
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