LOX-1 Rat anti-Mouse, Clone: 214012, Invitrogen
Rat Monoclonal Antibody
Manufacturer: Invitrogen MA523895
This antibody does not cross-react with recombit human LOX&No.x2011;1. Reconstitute at 0.5 mg/mL in sterile PBS.Low-density lipoprotein (LDL) is the carrier protein for cholesterol in the blood. LDL binds to its receptor on the capillary walls and thereby mediates the uptake and clearence of cholesterol from the circulation. In atherosclerotic lesions oxidatively modified LDL is found and oxidized LDL is specifically recognized and ingested by macrophages via scavenger receptor A and CD36. Oxidized LDL may be a marker of atherosclerosis but the precise changes in oxidized LDL are not well described. MDA-oxidized LDL appear to be different from LDL oxidized by other means.
|PBS with 5% trehalose and No Preservative|
|CLEC8A, LOX1, LOXIN, SCARE1, SLOX1,C-type lectin domain family 8 member A, hLOX-1, lectin-type oxidized LDL receptor 1, ox LDL receptor 1, oxidized low-density lipoprotein receptor 1, oxidized low-density lipoprotein receptor 1, soluble form, scavenger receptor class E, member 1|
|-20° C, Avoid Freeze/Thaw Cycles|
|Flow Cytometry, Western Blot|
|Mouse myeloma cell line NS0-derived recombit mouse LOX-1 Arg60-Ile363|
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