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LOX-1 Mouse anti-Human, Clone: 331212, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA524060

Catalog No. PIMA524060


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Description

Description

In direct ELISAs and Western blots, this antibody does not cross-react with recombit mouse LOX-1. Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.

Low-density lipoprotein (LDL) is the carrier protein for cholesterol in the blood. LDL binds to its receptor on the capillary walls and thereby mediates the uptake and clearence of cholesterol from the circulation. In atherosclerotic lesions oxidatively modified LDL is found and oxidized LDL is specifically recognized and ingested by macrophages via scavenger receptor A and CD36. Oxidized LDL may be a marker of atherosclerosis but the precise changes in oxidized LDL are not well described. MDA-oxidized LDL appear to be different from LDL oxidized by other means.
Specifications

Specifications

LOX-1
Monoclonal
0.5 mg/mL
PBS with 5% trehalose and No Preservative
P78380
CLEC8A, LOX1, LOXIN, SCARE1, SLOX1,C-type lectin domain family 8 member A, hLOX-1, lectin-type oxidized LDL receptor 1, ox LDL receptor 1, oxidized low-density lipoprotein receptor 1, oxidized low-density lipoprotein receptor 1, soluble form, scavenger receptor class E, member 1
Mouse
IgG2B
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
4973
Flow Cytometry, Neutralization, Western Blot
331212
Unconjugated
OLR1
Lyophilized
OLR1
Mouse myeloma cell line NS0-derived recombit human LOX-1/OLR1 Ser61-Gln273
Protein A/G
RUO
Antibody
Monoclonal
Human
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