anti-LOXL1, MaxPab™ Polyclonal, Abnova

Rabbit Polyclonal

Manufacturer: Abnova Corporation H00004016D01P

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Catalog No. 89-017-819

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    Antigen lysyl oxidase-like 1
    Conjugate Unlabeled
    Cross Reactivity Human
    Format Affinity Purified
    Host Species Rabbit
    Immunogen LOXL1 (NP_005567.2, 1 a.a. ∽574 a.a) full-length human protein.
    Purification Method Protein A column
    Quantity 100μg
    Regulatory Status RUO
    Primary or Secondary Primary
    Monoclonal or Polyclonal Polyclonal

    This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.

    Host Species: Rabbit
    Species Reactivity [for Features Main]: Human
    Immunogen: LOXL1 (NP_005567.2, 1 a.a. ~ 574 a.a) full-length human protein.

    Detection Antibody, Western Blotting

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