lysyl oxidase-like 1, Rabbit, Purified MaxPab™ Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against a full-length human LOXL1 protein.

Manufacturer: Abnova Corporation H00004016D01P

Catalog No. 89-017-819

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    Applications Western Blotting
    Formulation In 1X PBS, pH 7.4
    Gene LOXL1
    Gene Accession No. NM_005576.2
    Gene Alias LOL, LOXL
    Gene Symbols LOXL1
    Species Reactivity Human
    Storage Requirements Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
    Gene ID (Entrez) 4016
    Description lysyl oxidase-like 1
    Antigen lysyl oxidase-like 1
    Format Affinity Purified
    Host Species Rabbit
    Immunogen LOXL1 (NP_005567.2, 1 a.a. ∽574 a.a) full-length human protein.
    Purification Method Protein A column
    Quantity 100μg
    Regulatory Status RUO
    Primary or Secondary Primary
    Monoclonal or Polyclonal Polyclonal
    Conjugate Unlabeled
    Cross Reactivity Human

    This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq


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