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LRFN4 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA520699

Catalog No. PIPA520699


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Description

Description

A suggested positive control is rat brain tissue lysate. PA5-20699 can be used with blocking peptide PEP-0814.

LRFN4 is one of a family of five transmembrane glycoproteins that are highly expressed in neuronal tissues. LRFN proteins share leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family of proteins. Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while Lrfn2 and Lrfn5 expression was primarily restricted to more mature cells. LRFN1, -2, and -4 bound to PDZ domains of postsynaptic PSD95, re-distributing PSD95 to the cell periphery. It has been suggested that the Lrfn proteins play a role in the developing and/or mature vertebrate nervous system. At least two isoforms of LRFN4 are known to exist.
Specifications

Specifications

LRFN4
Polyclonal
Unconjugated
LRFN4
Liquid
LRFN4
a 14amino acid peptide near the carboxy terminus of human LRFN4.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q6PJG9, Q80XU8, D4ABX8
FIGLER6, SALM3, SALM3.; fibronectin type III, immunoglobulin and leucine rich repeat domains 6; leucine-rich repeat and fibronectin type-III domain-containing protein 4
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
225875, 688721, 78999
Documents
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