LRFN5 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA520700
A suggested positive control is EL4 cell lysate. PA5-20700 can be used with blocking peptide PEP-0815.LRFN5 is one of a family of five transmembrane glycoproteins that are highly expressed in neuronal tissues. LRFN proteins share leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family of proteins. Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while LRFN2 and LRFN5 expression was primarily restricted to more mature cells. LRFN1, -2, and -4 bound to PDZ domains of postsynaptic PSD95, re-distributing PSD95 to the cell periphery. It has been suggested that the Lrfn proteins play a role in the developing and/or mature vertebrate nervous system.
|A 16 amino acid peptide near the carboxy terminus of human LRFN5.|
|Antigen affinity chromatography|
|Human, Mouse, Rat|
|Immunohistochemistry, Western Blot|
|PBS with 0.02% sodium azide|
|Q96NI6, Q8BXA0, D4A1J9|
|C14orf146, FIGLER8, SALM5; fibronectin type III, immunoglobulin and leucine rich repeat domains 8; leucine-rich repeat and fibronectin type-III domain-containing protein 5|
|Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|145581, 238205, 314164|
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