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anti-LRIG1, Alexa Fluor 488, Polyclonal, R&D Systems™

Leucine-rich Repeats and Immunoglobulin-like Domains 1

Manufacturer:  R&D Systems FAB8140G

Catalog No. FAB8140G


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Description

Description

LRIG1 (leucine-rich repeat and Ig-like domain-containing-1) is a 145 kDa type I transmembrane glycoprotein that shares 45 - 50% amino acid (aa) identity with two other mammalian LRIG proteins. LRIG1 shows highest expression in subsets of glial cells in brain, and certain epithelia in liver, stomach, small intestine and skeletal muscle. Within the cell, LRIG1 is expressed in the perinuclear region as well as on the surface. LRIG1 binds ErbB receptors and promotes their ubiquitination, internalization and destruction.

Host Species: Sheep
Isotype: IgG
Species Reactivity: Hu
Immunogen: Human embryonic kidney cell line HEK293-derived recombinant human LRIG1. Ala35-Ser779; Accession Number Q96JA1

Applications:

Flow Cytometry

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The product is shipped with polar packs.

Specifications

Specifications

LRIG1
Alexa Fluor 488
Supplied in a saline solution containing BSA and Sodium Azide. with Sodium Azide
Purified
LRIG1
Human embryonic kidney cell line HEK293-derived recombinant human LRIG1 Ala35-Ser779 Accession # Q96JA1
Antigen Affinity-purified
RUO
Primary
26018
Human
Flow Cytometry
Flow Cytometry 5 uL/10^6 cells
Q96JA1
D6Bwg0781e, Img, LIG1, LIG-1
Sheep
IgG
100 Tests
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 degreesC as supplied.
Polyclonal
Detects human LRIG1 in direct ELISAs. In direct ELISAs, approximately 10% cross-reactivity with recombinant mouse LRIG1 and and less 1% cross-reactivity with recombinant human LRIG3 is observed.
SDS
Documents
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