LRP6 Mouse anti-Human, Clone: 255302, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA523950
Reconstitute in sterile PBS to a final concentration of 0.5 mg/mL.This gene encodes a member of the low density lipoprotein receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- processing but the precise locations of the cleavage sites have not been determined.
|PBS with 5% trehalose and No Preservative|
|LRP6, low density lipoprotein receptor-related protein 6, low density lipoprotein-related protein 6, ADCAD2, FLJ90062, FLJ90421, lpr6|
|-20° C, Avoid Freeze/Thaw Cycles|
|Flow Cytometry, Immunocytochemistry, Immunofluorescence|
|Mouse myeloma cell line NS0-derived recombit human LRP-6 Ala20-Pro1368|
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