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LRP6 Rat anti-Mouse, Clone: 290913, Invitrogen™

Rat Monoclonal Antibody

Manufacturer:  Invitrogen MA523995

Catalog No. PIMA523995


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Description

Description

In direct ELISAs, this antibody shows approximately 50-60% cross-reactivity with recombit human (rh) LRP-6 and no cross-reactivity with rhLDL R. Reconstitute at 0.5 mg/mL in sterile PBS.

This gene encodes a member of the low density lipoprotein receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- processing but the precise locations of the cleavage sites have not been determined.
Specifications

Specifications

LRP6
Monoclonal
0.5 mg/mL
PBS with 5% trehalose and No Preservative
O88572
LRP6, low density lipoprotein receptor-related protein 6, low density lipoprotein-related protein 6, ADCAD2, FLJ90062, FLJ90421, lpr6
Rat
IgG2B
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
16974
Western Blot
290913
Unconjugated
Lrp6
Lyophilized
LRP6
CHO-derived recombit mouse LRP-6 Met1-Pro1368
Protein A/G
RUO
Antibody
Monoclonal
Mouse
Documents
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