LRRC19 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA520914
A suggested positive control is K562 cell lysate. PA5-20914 can be used with blocking peptide PEP-1028.LRRC19 is a member of the extracellular leucine-rich repeat superfamily, a family of proteins that are thought to have diverse functions such as cell adhesion, signaling, and innate immunity. LRRC19 is closely related to the Toll-like receptors (TLRs), especially TLR3. LRRC19 does not contain a cytoplasmic Toll/IL-1 receptor (TIR) domain, but can activate NF-kappa-B and induce the production of proinflammatory cytokines after stimulation with the TLR3 and other TLR ligands, suggesting that LRRC19 may play a role in the recognition and the response to certain pathogenic microorganisms. LRRC19 has also been suggested to be a potential biomarker for pancreatic tumor sensitivity to the anti-cancer, small molecule Src inhibitor AZD0530.
|A 17 amino acid peptide near the carboxy terminus of human LRRC19.|
|Antigen affinity chromatography|
|Immunocytochemistry, Immunofluorescence, Western Blot|
|PBS with 0.02% sodium azide|
|leucine-rich repeat-containing protein 19|
|Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
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