Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

LRRFIP1 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523445

Catalog No. PIPA523445


Add to cart

Description

Description

Leucine-rich repeat FLI-I interacting protein 1 (LRRFIP1/FLAP-1) is a MyD88-interacting signal protein which mediates either induction or repression of TLR signaling. Flap-1 directly interacts with ß-catenin and activates ß-catenin-dependent transcription activity. Flap-1 or LRRFIP1 was also shown to bind the TNF- -308 promoter polymorphism site, suggesting its possible role in the regulation of TNF- production. FLAP-1 along with LRRFIP2 and FLIIH serve as a balance in coordinating inflammatory response after infection, and may act as a novel target in the control of agonist-induced TLR-mediated inflammatory and autoimmune diseases.
Specifications

Specifications

LRRFIP1
Polyclonal
Unconjugated
LRRFIP1
Liquid
LRRFIP1
Synthetic peptide (213 EERPEKDFTEKGSRNMPG 230) of LRRFIP1 protein.
Protein A
RUO
Antibody
Polyclonal
Human, Mouse
Western Blot
0.5 mg/mL
PBS with 0.05% BSA and 0.05% sodium azide
Q32MZ4, Q3UZ39
FLAP-1, FLAP1, FLIIAP1, GCF-2, GCF2, HUFI-1, TRIP, GC-binding factor 2, LRR FLII-interacting protein 1, NEDD8-conjugating enzyme, TAR RNA-interacting protein, leucine-rich repeat flightless-interacting protein 1
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
16978, 9208
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit