LRRFIP1 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA523445
DescriptionLeucine-rich repeat FLI-I interacting protein 1 (LRRFIP1/FLAP-1) is a MyD88-interacting signal protein which mediates either induction or repression of TLR signaling. Flap-1 directly interacts with ß-catenin and activates ß-catenin-dependent transcription activity. Flap-1 or LRRFIP1 was also shown to bind the TNF- -308 promoter polymorphism site, suggesting its possible role in the regulation of TNF- production. FLAP-1 along with LRRFIP2 and FLIIH serve as a balance in coordinating inflammatory response after infection, and may act as a novel target in the control of agonist-induced TLR-mediated inflammatory and autoimmune diseases.
|Synthetic peptide (213 EERPEKDFTEKGSRNMPG 230) of LRRFIP1 protein.|
|PBS with 0.05% BSA and 0.05% sodium azide|
|FLAP-1, FLAP1, FLIIAP1, GCF-2, GCF2, HUFI-1, TRIP, GC-binding factor 2, LRR FLII-interacting protein 1, NEDD8-conjugating enzyme, TAR RNA-interacting protein, leucine-rich repeat flightless-interacting protein 1|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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