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LRRFIP2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA521115

Catalog No. PIPA521115


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Description

Description

A suggested positive control is rat colon lysate. PA5-21115 can be used with blocking peptide PEP-1229.

The leucine-rich repeat FLI-I-interacting protein 2 (LRRFIP2), like the related protein LRRFIP1, was identified in a yeast two-hybrid system through binding to the LRR domain of human FLI. It can activate the Wnt signaling pathway in cultured cells and is thought to be a component of the Wnt signaling pathway that modulates Wnt signaling through interactions with Disheveled to increase the cellular levels and transcription activity of beta-catenin. LRRFIP2 has recently been characterized as a positive regulator of the TLR4 signaling pathway for activating NF-kappa-B during the early host response to LPS stimulation through binding to the TLR adaptor protein MyD88, and that this interaction with MyD88 is governed by phosphorylation of specific residues in LRRFIP2.
Specifications

Specifications

LRRFIP2
Polyclonal
Unconjugated
LRRFIP2
Liquid
LRRFIP2
A 17 amino acid peptide near the carboxy terminus of human LRRFIP2.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q9Y608, Q91WK0, Q4V7E8
HUFI-2; LRR FLII-interacting protein 2; leucine-rich repeat flightless-interacting protein 2
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
301035, 71268, 9209
Documents
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