TRPM7 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA528101

Catalog No. PIPA528101

Description

PA5-28101 targets LTRPC7 in WB applications and shows reactivity with Human samples. The PA5-28101 immunogen is synthetic peptide corresponding to a region within amino acids 1802 and 1865 of Human LTRPC7. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

TRPCs, mammalian homologs of the Drosophila transient receptor potential (trp) protein, are ion channels that are thought to mediate capacitative calcium entry into the cell. TRP-PLIK is a protein that is both an ion channel and a kinase. As a channel, it conducts calcium and monovalent cations to depolarize cells and increase intracellular calcium. As a kinase, it is capable of phosphorylating itself and other substrates. The kinase activity is necessary for channel function, as shown by its dependence on intracellular ATP and by the kinase mutants.

Specifications

• Antigen: TRPM7
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene Accession No.: Q96QT4
• Gene Symbols: TRPM7
• Immunogen: Synthetic peptide corresponding to a region within amino acids 1802 and 1865 of Human LTRPC7
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Gene: TRPM7
• Gene Alias: CHAK, CHAK1, LTRPC7, TRP-PLIK, LTRPC ion channel family member 7, LTrpC-7, channel-kinase 1, long transient receptor potential channel 7, transient receptor potential cation channel subfamily M member 7, transient receptor potential-phospholipase C-interacting kinase
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 54822
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid